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	Bowel Health
	Diabetes and Cholesterol Rapid
	Kidney Health
	Advanced Well Woman

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Hereditary Cancer DNA Test

Name: Hereditary Cancer DNA Test
SKU: 11102
Price: 549.00 GBP
Availability: InStock

£549.00

The best value Cancer DNA test available – check your DNA for your risk of developing 12 different cancers.

Our complete Hereditary Cancer DNA test checks a small saliva sample to ascertain your risk of developing a range of 12 different cancers.

Over 70 genes including checks for the BRCA 1 & BRCA 2 genes, which lead to increased risk of breast and ovarian cancers.

Suitable for males and females, 18 and over, with no initial consultation required.

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Hereditary Cancer DNA Test

£549.00

Collection Method:

Saliva Sample Home Test Kit

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£549

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Our home DNA test is the perfect way to check your genetic risk of developing a range of different cancers.

1 in 2 people in the UK will develop cancer.

Commonly cancers can be caused by lifestyle and habits, such as smoking or not using sunscreen. However cancer can also be brought on, or made worse, by mutations in your genes.

Our DNA test is completed at home using a small saliva sample, and tested in a leading laboratory to understand you risk of developing:

Breast cancer
Ovarian cancer
Bowel cancer, commonly known as Colorectal
Melanoma
Thyroid
Pancreatic
Prostate
Gastric (stomach)
Renal
Endometrial
Uterine
Non Melanoma skin cancer

Knowing your risk means you can take action now to ensure you stay healthy for longer – such as regularly checking your breasts at home and going for regular screening.

You do not need an initial consultation to take this test.

Get your DNA results in 3 simple steps:

Order your test kit online for delivery to your door.
Provide a saliva sample and post it back to our laboratory for analysis – postage is free.
Our experts analyse your sample and send your results via email in 2-4 weeks.

It’s never been simpler to understand your health and risk of cancer, and our best value DNA test is the ideal way to check your genetic health today.

Our test specifically looks for mutations in genes associated with a number of Hereditary Cancers, including:

Gene	OMIM (Gene)	Associated Diseases (OMIM)
APC	611731	Colorectal cancer, somatic
		Gastric cancer, somatic
		Gastric adenocarcinoma and proximal polyposis of the stomach
		Desmoid disease, hereditary
		Adenomatous polyposis coli
		Gardner syndrome
		Brain tumor-polyposis syndrome 2
		Hepatoblastoma, somatic
ATM	607585	Breast cancer, susceptibility to
ATM	607585	Ataxia-telangiectasia
AXIN2	604025	Oligodontia-colorectal cancer syndrome
AXIN2	604025	Colorectal cancer, somatic
BAP1	603089	Tumor predisposition syndrome
		Kury-Isidor syndrome
		Uveal melanoma, susceptibility to, 2
BARD1	601593	Breast cancer, susceptibility to
BLM	604610	Bloom syndrome
BMPR1A	601299	Polyposis, juvenile intestinal
		Juvenile polyposis syndrome, infantile form
		Polyposis syndrome, hereditary mixed, 2
BRCA1	113705	Breast-ovarian cancer, familial, 1
		Pancreatic cancer, susceptibility to, 4
		Fanconi anemia, complementation group S
BRCA2	600185	Prostate cancer
		Breast-ovarian cancer, familial, 2
		Glioblastoma 3
		Wilms tumor
		Pancreatic cancer 2
		Breast cancer, male, susceptibility to
		Fanconi anemia, complementation group D1
		Medulloblastoma
BRIP1	605882	Fanconi anemia, complementation group J
BRIP1	605882	Breast cancer, early-onset, susceptibility to
CDH1	192090	Prostate cancer, susceptibility to
		Breast cancer, lobular
		Blepharocheilodontic syndrome 1
		Ovarian cancer, somatic
		Gastric cancer, hereditary diffuse, with or without cleft lip and/or palate
		Endometrial carcinoma, somatic
CDK4	123829	Melanoma, cutaneous malignant, 3
CDKN2A	600160	Melanoma and neural system tumor syndrome
		Melanoma-pancreatic cancer syndrome
		Melanoma, cutaneous malignant, 2
CHEK2	604373	Prostate cancer, familial, susceptibility to
		Colorectal cancer, susceptibility to
		Breast cancer, susceptibility to
		Osteosarcoma, somatic
		Li-Fraumeni syndrome
DICER1	606241	Pleuropulmonary blastoma
		Goiter, multinodular 1, with or without Sertoli-Leydig cell tumors
		GLOW syndrome, somatic mosaic
		Rhabdomyosarcoma, embryonal, 2
DIS3L2	614184	Perlman syndrome
EPCAM	185535	Colorectal cancer, hereditary nonpolyposis, type 8
EPCAM	185535	Diarrhea 5, with tufting enteropathy, congenital
FANCC	613899	Fanconi anemia, complementation group C
FH	136850	Fumarase deficiency
FH	136850	Leiomyomatosis and renal cell cancer
FLCN	607273	Birt-Hogg-Dube syndrome
		Pneumothorax, primary spontaneous
		Renal carcinoma, chromophobe, somatic
		Colorectal cancer, somatic
GALNT12	610290	Colorectal cancer, susceptibility to, 1
HOXB13	604607	Prostate cancer, hereditary, 9
KIT	164920	Gastrointestinal stromal tumor, familial
		Germ cell tumors, somatic
		Piebaldism
		Leukemia, acute myeloid, somatic
		Mastocytosis, systemic, somatic
		Mastocytosis, cutaneous
MC1R	155555	[Skin/hair/eye pigmentation 2, blond hair/fair skin]
		[Skin/hair/eye pigmentation 2, red hair/fair skin]
		Melanoma, cutaneous malignant, 5
		UV-induced skin damage
		[Analgesia from kappa-opioid receptor agonist, female-specific]
		Albinism, oculocutaneous, type II, modifier of
MEN1	613733	Multiple endocrine neoplasia 1
MET	164860	Hepatocellular carcinoma, childhood type, somatic
		Deafness, autosomal recessive 97
		Osteofibrous dysplasia, susceptibility to
		Renal cell carcinoma, papillary, 1, familial and somatic
		Arthrogryposis, distal, type 11
MITF	156845	Melanoma, cutaneous malignant, susceptibility to, 8
		Waardenburg syndrome, type 2A
		Waardenburg syndrome/ocular albinism, digenic
		Tietz albinism-deafness syndrome
		COMMAD syndrome
MLH1	120436	Mismatch repair cancer syndrome 1
		Muir-Torre syndrome
		Colorectal cancer, hereditary nonpolyposis, type 2
MLH3	604395	Colorectal cancer, somatic
		Endometrial cancer, susceptibility to
		Colorectal cancer, hereditary nonpolyposis, type 7
MRE11	600814	Ataxia-telangiectasia-like disorder 1
MSH2	609309	Muir-Torre syndrome
		Colorectal cancer, hereditary nonpolyposis, type 1
		Mismatch repair cancer syndrome 2
MSH3	600887	Endometrial carcinoma, somatic
MSH3	600887	Familial adenomatous polyposis 4
MSH6	600678	Colorectal cancer, hereditary nonpolyposis, type 5
		Endometrial cancer, familial
		Mismatch repair cancer syndrome 3
MUTYH	604933	Adenomas, multiple colorectal
MUTYH	604933	Gastric cancer, somatic
NBN	602667	Aplastic anemia
		Leukemia, acute lymphoblastic
		Nijmegen breakage syndrome
NF1	613113	Watson syndrome
		Leukemia, juvenile myelomonocytic
		Neurofibromatosis, type 1
		Neurofibromatosis, familial spinal
		Neurofibromatosis-Noonan syndrome
NTHL1	602656	Familial adenomatous polyposis 3
PALB2	610355	Pancreatic cancer, susceptibility to, 3
		Fanconi anemia, complementation group N
		Breast cancer, susceptibility to
PMS2	600259	Colorectal cancer, hereditary nonpolyposis, type 4
PMS2	600259	Mismatch repair cancer syndrome 4
POLD1	174761	Colorectal cancer, susceptibility to, 10
POLD1	174761	Mandibular hypoplasia, deafness, progeroid features, and lipodystrophy syndrome
POLE	174762	Colorectal cancer, susceptibility to, 12
		IMAGE-I syndrome
		FILS syndrome
POT1	606478	Melanoma, cutaneous malignant, susceptibility to, 10
POT1	606478	Glioma susceptibility 9
PRSS1	276000	Pancreatitis, hereditary
PTCH1	601309	Basal cell carcinoma, somatic
		Holoprosencephaly 7
		Basal cell nevus syndrome
PTEN	601728	Cowden syndrome 1
		Lhermitte-Duclos syndrome
		Macrocephaly/autism syndrome
		Glioma susceptibility 2
		Meningioma
		Prostate cancer, somatic
RAD50	604040	Nijmegen breakage syndrome-like disorder
RAD51C	602774	Fanconi anemia, complementation group O
RAD51C	602774	Breast-ovarian cancer, familial, susceptibility to, 3
RAD51D	602954	Breast-ovarian cancer, familial, susceptibility to, 4
RET	164761	Hirschsprung disease, susceptibility to, 1
		Multiple endocrine neoplasia IIA
		Medullary thyroid carcinoma
		Pheochromocytoma
		Multiple endocrine neoplasia IIB
		Hirschsprung disease, protection against
		Central hypoventilation syndrome, congenital
RNF43	612482	Sessile serrated polyposis cancer syndrome
SDHA	600857	Neurodegeneration with ataxia and late-onset optic atrophy
		Cardiomyopathy, dilated, 1GG
		Leigh syndrome
		Mitochondrial respiratory chain complex II deficiency
		Paragangliomas 5
SDHAF2	613019	Paragangliomas 2
SDHB	185470	Pheochromocytoma
		Mitochondrial complex II deficiency, nuclear type 4
		Paragangliomas 4
		Paraganglioma and gastric stromal sarcoma
		Gastrointestinal stromal tumor
SDHC	602413	Paraganglioma and gastric stromal sarcoma
		Gastrointestinal stromal tumor
		Paragangliomas 3
SDHD	602690	Mitochondrial complex II deficiency
		Paraganglioma and gastric stromal sarcoma
		Paragangliomas 1, with or without deafness
		Mitochondrial complex II deficiency, nuclear type 3
		Pheochromocytoma
SMAD4	600993	Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome
		Pancreatic cancer, somatic
		Myhre syndrome
		Polyposis, juvenile intestinal
SMARCA4	603254	Coffin-Siris syndrome 4
SMARCA4	603254	Rhabdoid tumor predisposition syndrome 2
STK11	602216	Peutz-Jeghers syndrome
		Melanoma, malignant, somatic
		Testicular tumor, somatic
		Pancreatic cancer, somatic
TP53	191170	Hepatocellular carcinoma, somatic
		Bone marrow failure syndrome 5
		Basal cell carcinoma 7
		Nasopharyngeal carcinoma, somatic
		Choroid plexus papilloma
		Glioma susceptibility 1
		Pancreatic cancer, somatic
		Breast cancer, somatic
		Li-Fraumeni syndrome
		Adrenocortical carcinoma, pediatric
		Osteosarcoma
		Colorectal cancer
TSC1	605284	Lymphangioleiomyomatosis
		Focal cortical dysplasia, type II, somatic
		Tuberous sclerosis-1
TSC2	191092	Focal cortical dysplasia, type II, somatic
		Lymphangioleiomyomatosis, somatic
		Tuberous sclerosis-2
VHL	608537	Pheochromocytoma
		von Hippel-Lindau syndrome
		Renal cell carcinoma, somatic
		Erythrocytosis, familial, 2
WT1	607102	Denys-Drash syndrome
		Mesothelioma, somatic
		Frasier syndrome
		Meacham syndrome
		Wilms tumor, type 1
		Nephrotic syndrome, type 4
XRCC2	600375	Spermatogenic failure
		Fanconi anemia, complementation group U
		Premature ovarian failure 17
XRCC3	600675	Breast cancer, susceptibility to
XRCC3	600675	Melanoma, cutaneous malignant, 6

What’s included?

Genetic Cancer Risk
12 bio markers

Learn More

Frequently Asked Questions

Placing an order

Which test should I choose?

You should choose the test that is right for your needs, symptoms and health concerns. Details of the health biomarkers included in each test can be found on the test pages on our website. If you want an all-round health test, we recommend the Well Woman or Well Man tests which provide the widest range of biomarkers and the best value to check numerous areas of your health.

I’ve just paid, can I change my order?

If you need to make any changes to your order or your booking, please contact us and we will see what we can do to help you. Be aware that if you need to cancel your test, you may be charged a cancellation fee.

Can I order a test for someone else?

Yes – please add their details when making your booking, and then your details at the checkout if you need to. Please be aware that our tests are only for customers aged 18 or over.

How often should I take a test?

We believe it’s most effective to monitor your health regularly over time. So we recommend taking your test every three months. This is the amount of time it typically takes to see the impact of health and lifestyle changes.

Completing a Home Test

What if my kit needs other samples, such as urine?

If your test requires other samples, such as blood and urine or saliva, please follow the instructions within the kit to collect the required samples correctly. If you have any problems, please contact our helpful team.

After your test

How do I book a follow up GP consultation?

You can find out more about our online GP Consultation Service here. Appointments are available at your convenience, from 8am to 8pm, 365 days a year.

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